Theoretical Study on Specific Loss Power and Heating Temperature in CoFe2O4 Nanoparticles as Possible Candidate for Alternative Cancer Therapy by Superparamagnetic Hyperthemia

In this paper, we present a theoretical study on the maximum specific loss power in admissible biological limit (PsM)l for CoFe2O4 ferrimagnetic nanoparticles, as possible candidate alternative and non-invasive cancer therapy by superparamagnetic hyperthermia. The heating time of nanoparticles (?to) at optimum temperature approx. 43 °C efficient destruction tumor cells short period time, was also studied. We found PsM (as result superparamegnetic relaxation nanoparticles) very small diameters (Do), situated range 5.88–6.67 nm, with frequencies (fl) wide values 83–1000 kHz, respectively. Additionally, optimal (To) obtained magnetic field H, 5–60 kA/m, corresponding times were intervals ~0.3–44 s, depending volume packing fraction (?) nanoparticles. results, well amplitude H frequency f external alternating which hyperthermia can be obtained, are great practical benefits case hyperthermia, demonstrate that successfully used superaparamagnetic addition, size (only few nm) will lead to two major via namely: (i) possibility intracellular is much more effective due ability destroy from within (ii) reduced cell toxicity.